Strategies for providing toxicological & therapeutic insights about cannabinoid biology using zebrafish. Cannabinoid biology may be elucidated in the zebrafish using a tandem of
pharmacological and genetic approaches. Pharmacological approaches should include investigations of endocannabinoids, phytocannabinoids, and synthetic cannabinoids. Genetic
approaches should include the use of targeted genome editing approaches such as a custom nuclease technology, as well as untargeted genome editing approaches such as transposon
systems. The use of pharmacological and genetic approaches with the zebrafish model will reveal novel toxicological and therapeutic insights about cannabinoid biology.